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IgE and T-cell responses to house dust mite allergen componentsRecent studies with synthetic peptides representing allergens and non-allergenic house dust mite proteins now offer new research avenues on HDM induced immune responses
Research
Epigenetic dysregulation of naive CD4+ T-cell activation genes in childhood food allergyOur data indicate epigenetic dysregulation in the early stages of signal transduction through the T cell receptor complex, and likely reflects pathways modified by gene-environment interactions in food allergy
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Relevance of Aboriginal Peer-Led Parent Support: Strengthening the Child Environment in Remote AreasThis research highlights the critical emerging role of peer support workers in home visiting family support in a remote area of Australia
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Rhinovirus is the most common virus and rhinovirus-C is the most common species in paediatric intensive care respiratory admissionsThis is the first report examining the role of different rhinovirus species in ARIs in children admitted to a tertiary PICU
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Meta-taxonomic analysis of prokaryotic and eukaryotic gut flora in stool samples from visceral leishmaniasis cases and endemic controls in Bihar State IndiaWe evaluate a meta-taxonomic approach to determine the composition of prokaryotic and eukaryotic gut microflora using sequencing of 16S RNA and 18S rRNA
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In Epigenomic Studies, Including Cell-Type Adjustments in Regression Models Can Introduce Multicollinearity, Resulting in Apparent Reversal of Direction of AssociationWhere cell types are highly correlated with other covariates in regression models, the statistical assumption of no multicollinearity may be violated
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Maternal Smoking During Pregnancy Induces Epigenetic Changes Into Adolescence, Independent of Postnatal Smoke Exposure and Is Associated With Cardiometabolic RiskThis study demonstrates a critical timing of cigarette smoke exposure over the life course for establishing persistent changes in DNA methylation into adolescence
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Glutathione S-Transferase Genotype Protects against in Utero Tobacco-linked Lung Function DeficitsCertain glutathione S-transferase genotypes may have protective effects against the long-term deficits in lung function associated with in utero tobacco exposure
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Viral respiratory infections and the oropharyngeal bacterial microbiota in acutely wheezing childrenBacterial airway microbiome is highly variable in early life and its role in wheeze remains less clear than viral influences
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Association between pregnant women's experience of stress and partners’ fly-in-fly-out workThere is some evidence that the pregnant partners of fly-in-fly-out workers perceive their lives to be more stressful