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Prevention of rheumatic fever and heart disease: Nepalese experience

Historically, many young people suffered severe valvular disease and died awaiting heart valve replacement.

A conceptual framework for comprehensive rheumatic heart disease control programs

The World Health Organization, World Heart Federation, and other organizations recommend comprehensive control programs for rheumatic fever (RF) and...

Benzathine penicillin G for the management of RHD: Concerns about quality and access, and opportunities for intervention and improvement

Benzathine penicillin G is an important antibiotic for the treatment and prevention of group A streptococcal infections associated with rheumatic fever and...

The 5 × 5 path toward rheumatic heart disease control: Outcomes from the third rheumatic heart disease forum

This editorial viewpoint regarding the outcomes from the third global Rheumatic Heart Disease Forum intends to carry forward dialogue & engage new...

Rheumatic heart disease: Tools for implementing programmes

This article discusses the World Health Organization program for monitoring & managing rheumatic heart disease.

Post-infectious group A streptococcal autoimmune syndromes and the heart

ARF is a classical example of an autoimmune syndrome and is of particular immunological interest because it follows a known antecedent infection with group A...

Comparison of approaches to rheumatic fever surveillance across Organisation for Economic Co-operation and Development countries.

Rheumatic fever (RF) prevention, control and surveillance are increasingly important priorities in New Zealand (NZ) and Australia.

Sore throat: Is it such a big deal anymore?

This review article addresses the driving factors associated with diagnosis and treatment of sore throats caused by Group A streptococcus.

Transiently increased IgE responses in infants and pre-schoolers receiving only (DTaP) vaccines compared to those initially receiving at least one dose of DTwP vaccine

Confirm the generalised IgE-trophic activity of the DTaP vaccine in pre-schoolers and demonstrate similar (albeit transient) effects in infants

Status of research and development of vaccines for Streptococcus pyogenes

Vaccines against Streptococcus pyogenes are considered as impeded vaccines because of a number of crucial barriers to development