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Research

Effectiveness of public health interventions in reducing the prevalence of Opisthorchis viverrini: a protocol for systematic review and network meta-analysis

The carcinogenic liver fluke Opisthorchis viverrini is a major public health problem in the Mekong basin region. The liver flukes can induce cholangiocarcinoma, a bile duct cancer that causes a significant burden of mortality and economic loss. Various public health interventions have been conducted to reduce opisthorchiasis but the prevalence of O. viverrini remains high in endemic regions.

Research

Antifungal prescribing in neonates: Using national point prevalence survey data from Australia

We describe contemporary antifungal use in neonates, with point-prevalence survey data from the National Antimicrobial Prescribing Survey across Australian hospitals from 2014 to 2018.

Research

Spatio-temporal patterns of childhood pneumonia in Bhutan: a Bayesian analysis

Pneumonia is one of the top 10 diseases by morbidity in Bhutan. This study aimed to investigate the spatial and temporal trends and risk factors of childhood pneumonia in Bhutan.

Research

Methods for modelling excess mortality across England during the COVID-19 pandemic

Excess mortality is an important measure of the scale of the coronavirus-2019 pandemic. It includes both deaths caused directly by the pandemic, and deaths caused by the unintended consequences of containment such as delays to accessing care or postponements of healthcare provision in the population. In 2020 and 2021, in England, multiple groups have produced measures of excess mortality during the pandemic.

Research

Clinical predictors of severe dengue: a systematic review and meta-analysis

Severe dengue is a life-threatening complication; rapid identification of these cases, followed by adequate management is crucial to improve the clinical prognosis. Therefore, this study aimed to identify risk factors and predictors of severe dengue.

News & Events

Landmark study halves skin infections in remote Aboriginal kids

Led by The Kids Research Institute Australia and Aboriginal health organisations in close partnership with nine Aboriginal communities in Western Australia’s Kimberley region, the five-year SToP Trial set out to identify the best possible methods to See, Treat and Prevent painful skin sores and scabies.

Research

The Host-Pathogen Interactions and Epicellular Lifestyle of Neisseria meningitidis

Neisseria meningitidis is a gram-negative diplococcus and a transient commensal of the human nasopharynx. It shares and competes for this niche with a number of other Neisseria species including N. lactamica, N. cinerea and N. mucosa. Unlike these other members of the genus, N. meningitidis may become invasive, crossing the epithelium of the nasopharynx and entering the bloodstream, where it rapidly proliferates causing a syndrome known as Invasive Meningococcal Disease.

Research

The global burden of sore throat and group A Streptococcus pharyngitis: A systematic review and meta-analysis

Contemporary data for the global burden of sore throat and group A Streptococcus (Strep A) pharyngitis are required to understand the frequency of disease and develop value propositions for Strep A vaccines.

News & Events

Trial tests which COVID-19 booster combos ‘boost’ immunity

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News & Events

Nasal spray to prevent ear infections closer to fruition thanks to major grant

A nasal spray that could potentially prevent childhood ear infections and reduce antibiotic use is a step closer to clinical trials thanks to a $500,000 CUREator grant.

News & Events

RSV rates skyrocket among Aboriginal babies

Experts are warning Aboriginal parents in Western Australia with newborn babies to be vigilant about Respiratory Syncytial Virus (RSV) as winter progresses.

News & Events

The Kids Ear Health researcher named finalist in Australia’s top science prizes

Paediatric audiologist Associate Professor Chris Brennan-Jones has been announced as a finalist for the country’s leading national science awards – the Australian Museum Eureka Prizes.

News & Events

Prestigious fellowship to help end the cycle of painful ear infections

A The Kids Research Institute Australia ear health researcher has received a prestigious national fellowship to support her search for new therapies to improve the lives of kids who suffer repeat middle ear infections.

News & Events

The Kids infectious diseases researcher named a WA Young Tall Poppy

A The Kids researcher focused on ensuring kids are protected from infectious diseases will be named among WA’s most outstanding young scientists at the upcoming 2021 Young Tall Poppy Science Awards.

News & Events

New research prepares for COVID-19 vaccine roll-out

As the world waits for a COVID-19 vaccine Perth researchers are getting one step ahead – embarking on a new study designed to prepare parents and government for a potential Australia-wide vaccination program.

News & Events

Perth’s Aboriginal babies show first signs of ear disease at just eight weeks

The Kids Research Institute Australia researchers have found close to 40 per cent of Aboriginal babies begin to develop middle ear infections between two and four months of age in a first of its kind study in metropolitan Perth.

News & Events

Kids hip hop to stop painful skin infections in the Kimberley region

The Kids Research Institute Australia researchers have launched the Hip Hop 2 SToP video featuring school kids participating in their SToP Trial project designed to see, treat and prevent skin infections in WA’s Kimberley region.