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Iatrogenic hypoglycaemia is one of the main limiting factors in the glycaemic management of diabetes. It causes negative biological, psychological, and social consequences in most people with type 1 diabetes and in many with advanced type 2 diabetes. This chapter explores physiological homeostatic mechanisms that prevent hypoglycaemia through glucose counter-regulation, before discussing specific acquired defects of glucose counter-regulation in diabetes, which provides an insight into risk factors for hypoglycaemia.
To compare HbA1c and clinical outcomes in adolescents and young adults with type 1 diabetes, with or without celiac disease.
Community sport coaches in Western Australia lack an understanding, the confidence, and knowledge in supporting young people with Type 1 diabetes (T1D). This study aims to identify what T1D educational resources are required to upskill coaches in Western Australia.
High protein high fat meals are considered “difficult” foods because they can cause prolonged hyperglycemia after ingestion. The potential of hybrid closed loop therapy in managing postprandial glucose excursions with these difficult foods remains unknown. This pilot study aimed to explore the impact of manual mode in standard insulin pump therapy and auto mode with hybrid closed loop pump therapy in managing glucose excursions caused by HPHF foods and to obtain feedback from families about each mode.
If the gut becomes damaged it may not be able to process the foods that we eat as well as it used to. This may also affect how we look after diabetes.
This study is looking for the causes of type 1 diabetes, so that we can find ways to prevent it. We will follow many women around Australia during pregnancy until early childhood, looking at the child's birth, environment and genes.
A register which stores demographic and clinical data on all patients attending the diabetes clinic at Princess Margaret Hospital
The purpose of this randomized clinical trial is to determine whether the use of the BIB aids weight loss in obese adolescents.
To conduct an analysis of children with TIDM’s cognitive profile at an age in which both cognition and cortical development are still maturing
Investigating changes in retinopathy, aortic intima media thickness & heart rate variability, indicators of macrovascular disease & autonomic neuropathy