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The ACEFA NHMRC Centre of Research Excellence aims to support the timely, effective response to epidemic diseases in Australia through real-time data analytics, modelling, and forecasting.
Following widespread exposure to Omicron variants, SARS-CoV-2 has transitioned to endemic circulation. Populations now have diverse infection and vaccination histories, resulting in heterogeneous immune landscapes. Careful consideration of the value of ongoing vaccination is required through the post-Omicron phase of COVID-19 management to minimise disease burden.