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Research

How ‘healthy’ do children really need to be? Going beyond the limits

The authors assessed the impact of including preschool‐aged children with a history of preterm birth, early life wheeze, asthma diagnoses and/or recent respiratory symptoms in healthy reference ranges for respiratory impedance using the forced oscillation technique (FOT).

Research

Analysis of expression of FLI1 and MMP1 in American cutaneous leishmaniasis caused by Leishmania braziliensis infection

MMP1 is regulated by factors other than FLI1, and that the influence of IL-6 on MMP1 was independent of its effect on FLI1 in Leishmania braziliensis

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Association Between Family Characteristics and the Effect of Timing of Regular Egg Introduction in Infant Egg Allergy

A recent systematic review of 5 randomized clinical trials, found that early egg introduction was associated with reduced egg allergy.

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The psychosocial burden of childhood overweight and obesity: evidence for persisting difficulties in boys and girls

Overweight and obese children reported greater psychosocial distress than healthy weight children, and these differences were more pronounced for girls than boys.

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Australian children living with rare diseases: experiences of diagnosis and perceived consequences of diagnostic delays

Parents of children living with rare chronic and complex diseases have called for better education and resourcing of health professionals

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Comparison of outcomes following a cytological or histological diagnosis of malignant mesothelioma

This study examines survival differences between patients with epithelioid MM diagnosed by cytology only and other subtypes diagnosed by histology.

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Chest imaging in cystic fibrosis studies: What counts, and can be counted?

The aim of this study is to characterize the role of currently available CT and MRI markers in clinical studies, and to discuss challenges with CF studies.

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The Diverse Risk Profiles of Persistently Absent Primary Students: Implications for Attendance Policies in Australia

Understanding variations in risk profiles among persistently non-attending children will inform the development of absence interventions.

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Air trapping in early cystic fibrosis lung disease-Does CT tell the full story?

Mosaic attenuation on expiratory chest computed tomography (CT) is common in early life cystic fibrosis (CF) and often referred to as "air trapping"

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Irreversible growth plate fusions in children with medulloblastoma treated with a targeted hedgehog pathway inhibitor

We report on 3 children treated with vismodegib who developed widespread growth plate fusions that persist long after cessation of therapy.