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Disruption of β-catenin/CBP signaling inhibits human airway epithelial-mesenchymal transition and repair.The airway epithelium of both children and adults with asthma is relatively undifferentiated characterized by a significantly increased proportion of...
Research
Pressurised metered dose inhaler-spacer technique in young children improves with video instructionRepeated video instruction over time improves inhaler technique in young children
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1,25-dihydroxyvitamin D3 enhances the ability of transferred CD4+ CD25+ cells to modulate T helper type 2-driven asthmatic responsesThe severity of allergic diseases may be modified by vitamin D. However, the immune pathways modulated by the active form of vitamin D, 1,25-dihydroxyvitamin D.
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Interactions between innate and adaptive immunity in asthma pathogenesis: new perspectives from studies on acute exacerbationsAtopic asthma, which is at its highest prevalence during childhood/young adulthood, represents the main focus of this review.
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The transient value of classifying preschool wheeze into episodic viral wheeze and multiple trigger wheezeA recently proposed method for classifying preschool wheeze is to describe it as either episodic (viral) wheeze or multiple trigger wheeze.
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Infection and the development of allergic diseaseAn improved understanding of the roles of protein kinases in intracellular signalling and disease progression has driven significant advances in protein...
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Influence of secular trends and sample size on reference equations for lung function testsThe aim of our study was to determine the contribution of secular trends and sample size to lung function reference equations, and establish the number...
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The role of GSTP1 polymorphisms and tobacco smoke exposure in children with acute asthmaThe glutathione S-transferase enzymes (GSTs) play an important role in the detoxification of environmental tobacco smoke (ETS), which contributes to airway infl
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Molecular characterization of Der p 10: A diagnostic marker for broad sensitization in house dust mite allergyTropomyosins represent clinically relevant seafood allergens but the role of mite tropomyosin
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CD4 allergen tetramersThe introduction of class II tetramers for identifying antigen-binding CD41 cells has lagged behind the use of class I tetramers because of difficulties...