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News & Events
New study to better understand how bronchiectasis develops during childhoodA new research project – the WA Paediatric Bronchiectasis Cohort Study – officially commenced this month with the aim of looking at children with bronchiectasis in Western Australia, like nine-year-old Holly (pictured), to better understand how this disease develops during childhood.
News & Events
Vertex grant to support research into treatment strategies for cystic fibrosis lung diseaseDr Daniel Laucirica, a research officer with the Wal-yan Respiratory Research Centre, will undertake new research into potential treatment strategies to prevent lung damage in people with cystic fibrosis (CF), under the mentorship of Associate Professor Anthony Kicic - made possible by a Vertex Cyst
News & Events
Respiratory research program recruits 400th participant, marking key milestoneIn September 2024, the Western Australian Epithelial Research Program (WAERP) reached a significant milestone by recruiting its 400th participant.
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Kids Easy Breathing Study KickstartsThe Kids Easy Breathing Study kickstarts this month, with the aim of finding out how the airway surface is different between infants who develop chronic lung disease after contracting bronchiolitis compared with those who don’t.
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Study shows climate change will devastate children’s health without fast global actionIncreased numbers of preterm births, higher incidence of respiratory disease and death, and more children in hospitals are some of the stark health outcomes the world is facing from the impacts of extreme climate change.
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Future research focus areas in kids’ lung healthYou play a vital role in determining Wal-yan’s research priorities in kids’ lung health over the next 10 years.
Our team uses AI to quickly analyse large amounts of genetic data to help discover alternate medications and improve existing treatments.
Research
Stability Considerations for Bacteriophages in Liquid Formulations Designed for NebulizationPulmonary bacterial infections present a significant health risk to those with chronic respiratory diseases including cystic fibrosis and chronic-obstructive pulmonary disease. With the emergence of antimicrobial resistance, novel therapeutics are desperately needed to combat the emergence of resistant superbugs.
Research
EVC-EVC2 complex stability and ciliary targeting are regulated by modification with ubiquitin and SUMOEllis van Creveld syndrome and Weyers acrofacial dysostosis are two rare genetic diseases affecting skeletal development. They are both ciliopathies, as they are due to malfunction of primary cilia, microtubule-based plasma membrane protrusions that function as cellular antennae and are required for Hedgehog signaling, a key pathway during skeletal morphogenesis.
Research
Insights into the associations between the gut microbiome, its metabolites and heart failureHeart failure (HF) is the end stage of most cardiovascular diseases and remains a significant health problem globally. We aimed to assess whether patients with left ventricular ejection fraction ≤45% had alterations in both the gut microbiome profile and production of associated metabolites when compared to a healthy cohort.