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News & Events
New Home for ORIGINSTelethon Kids Joondalup will be the new home for the ORIGINS research and data teams
News & Events
Digital support engagement needed for new MumsSystematic review explores engagement levels of digital tools during the perinatal period
News & Events
Calling All Budding ArtistsCalling all budding artists - submit your child's artwork to win!
News & Events
ORIGINS takes part in Aboriginal wellness expoThe ORIGINS Project participated in the inaugural Wadjak Northside Social Emotional Wellbeing Expo on 24 October at the Wadjak Northside Aboriginal Community Centre.
News & Events
ORIGINS researchers investigating gut health’s link to allergiesWith up to one in four Australian children now affected by allergic diseases, the potential for the ORIGINS SYMBA Study to positively impact future lives is immense.
News & Events
ORIGINS named in multi-million dollar investment towards child healthORIGINS named in multi-million investment towards child health
News & Events
Better Your BioMood: First Findings Published in Origins SubprojectPhoto source: Unsplashed The first findings in ORIGINS’ BioMood study have now been published, examining whether a Mediterranean diet can affect key
News & Events
Biobank funding supports valuable research resourcesFour The Kids Research Institute Australia-based biobanks which underpin a range of cancer, respiratory and early life research have received more than $450,000 in funding.
Research
PKC activation promotes maturation of cord blood T cells towards a Th1 IFN-γ propensityA significant number of babies present transiently with low protein kinase C zeta (PKCζ) levels in cord blood T cells, associated with reduced ability to transition from a neonatal Th2 to a mature Th1 cytokine bias, leading to a higher risk of developing allergic sensitisation, compared to neonates whose T cells have 'normal' PKCζ levels. However, the importance of PKCζ signalling in regulating their differentiation from a Th2 to a Th1 cytokine phenotype propensity remains undefined.
Research
The ORIGINS Project Biobank: A Collaborative Bio Resource for Investigating the Developmental Origins of Health and DiseaseEarly onset Non-Communicable Diseases (NCDs), including obesity, allergies, and mental ill-health in childhood, present a serious and increasing threat to lifelong health and longevity. The ORIGINS Project (ORIGINS) addresses the urgent need for multidisciplinary efforts to understand the detrimental multisystem impacts of modern environments using well-curated large-scale longitudinal biological sample collections.