Search
Research
Optimising a 6-plex tetanus-diphtheria-pertussis fluorescent bead-based immunoassaySmall volume assays are required for large-scale research studies and in particular paediatric trials, where multiple measures are required from a single sample. Fluorescent bead-based technology (Bioplex/Luminex) allows high through-put and simultaneous quantification of multiple analytes in a single test. This technology uses sets of microspheres, each with a unique spectral address that can be coated with a different antigen of interest.
Research
Immunogenicity and Safety of a 2 + 1 DTPa Priming Schedule in Australian Infants and the Impact of Maternally Derived Antibodies on Pertussis Antibody Responses up to 4 Years of AgeWe assessed the impact of maternally derived pertussis antibodies on infant responses to a 2 + 1 vaccine schedule (6 weeks, 12 weeks, and 12 months). Infants with baseline antibodies showed lower IgG responses following the primary vaccination series, but this did not impair booster responses at 4 years of age.
News & Events
Infectious Disease & Vaccination Public SeminarHear the facts about vaccination and infectious disease from some of Australia's leading experts: Professor Jonathan Carapetis, Dr Peter Richmond
News & Events
WANTED: 'Flu BustersHundreds of healthy volunteers are needed in Perth to test the effectiveness of a current 'flu vaccine.
Research
Toll-like receptor 7 and 8 polymorphisms: Associations with functional effects and cellular and antibody responses to measles virus and vaccineThe functionality and effects of TLR7 and TLR8 polymorphisms on cellular and antibody responses was investigated after the first measles vaccine dose.
Research
CD46 measles virus receptor polymorphisms influence receptor protein expressionDespite the availability of measles vaccines, infants continue to die from measles. Measles vaccine responses vary between individuals, and poor...
Research
The non-specific and sex-differential effects of vaccinesThe textbook view of vaccination is that it functions to induce immune memory of the specific pathogen components of the vaccine, leading to a quantitatively and qualitatively better response if the host is exposed to infection with the same pathogen
Research
Vaccination strategies to enhance immunity in neonatesProtection may be further improved by integrating these approaches, namely vaccinating the neonate under the cover of vertically transferred maternal immunity
Research
Response after one dose of monovalent influenza A (H1n1) 2009 vaccine in infants and children - preliminary reportTo assess the immunogenicity and safety of a 2009 influenza A(H1N1) vaccine in children.
Research
Trivalent influenza vaccine and febrile adverse events in australia, 2010: Clinical features and potential mechanismsIncreased numbers of children presenting with febrile adverse events following trivalent influenza vaccine (TIV) were noted in Australia in 2010.