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Research
It is more “unbalanced” than you thinkSébastien Malinge SM PhD Laboratory Head, Translational Genomics in Leukaemia, Ursula Kees Fellow (CCRF), Cancer Council WA Fellow (CCWA), Senior
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Confirmation of childhood acute lymphoblastic leukemia Variants, ARID5B and IKZF1, and interaction with parental environmental exposuresThe polygenic nature of childhood ALL predisposition together with the timing of environmental triggers may hold vital clues for disease etiology.
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Medulloblastoma Down Under 2013: a report from the third annual meeting of the International Medulloblastoma Working GroupMedulloblastoma is curable in approximately 70 % of patients. Over the past decade, progress in improving survival using conventional therapies has stalled...
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Risk of childhood acute lymphoblastic leukaemia following parental occupational exposure to pesticidesRisk of childhood acute lymphoblastic leukaemia following parental occupational exposure to pesticides.
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Interactions between acute lymphoblastic leukemia and bone marrow stromal cells influence response to therapyTo identify links between drug resistance and gene deregulation we used oligonucleotide microarray technology.
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Influence of wild-type MLL on glucocorticoid sensitivity and response to DNA-damage in pediatric acute lymphoblastic leukemiaRearrangement of the mixed-lineage leukemia gene (MLL) is found in 80% of infant acute lymphoblastic leukemia (ALL) and is associated with poor prognosis and re
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Gene-based outcome prediction in multiple cohorts of pediatric T-cell acute lymphoblastic leukemia: a Children's Oncology Group studyContinuous complete clinical remission in T-cell acute lymphoblastic leukemia (T-ALL) is now approaching 80% due to the implementation of aggressive...
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Glucocorticoid resistance in T-lineage acute lymphoblastic leukaemia is associated with a proliferative metabolismWe examined the baseline profile of a panel of T-ALL cell lines to determine factors that contribute to GC resistance without prior drug selection.
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Prenatal origins and health outcomes of male reproductive congenital anomalies diagnosed at birth and testicular cancer in adulthoodThis study involves record linkage of birth, birth defects, hospital, deaths and cancer data; with links to genealogy data to identify links between families.
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Australian Study of Causes of Acute Lymphoblastic Leukaemia in ChildrenAnalysing data collected between 2003 and 2007 in this national case-control study of the risk factors for childhood acute lymphoblastic leukaemia (ALL).