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The impact of a Mediterranean diet and physical activity in pregnancy on gestational weight gain and neonatal body composition at birth and 1 year of age

Desiree Silva MBBS, FRACP, MPH, PhD Co-Director, ORIGINS desiree.silva@thekids.org.au Co-Head, The ORIGINS Project Professor Desiree Silva is

The SYMBA Study - Promoting Gut Health (SYMBiosis) for Allergy prevention

Debbie Susan Desiree Palmer Prescott Silva BSc BND PhD MBBS BMedSci PhD FRACP MBBS, FRACP, MPH, PhD Head, Nutrition in Early Life Honorary Research

‘You Can Sort of Justify Having That Drink’: Australian Young Adults' Perspectives on the Appeal and Influence of ‘Better for You’ Alcohol Products

Alcohol industry publications reveal that the industry targets young people with better for you (BFY) marketing that promotes the nutrition and health-oriented aspects of some products, despite the inherent harms of alcohol consumption. This research investigated how young adults conceptualise the appeal of BFY alcohol products and their potential effect on consumption, and their opinions of the alcohol industry in the context of this marketing.

ORIGINS

ORIGINS is Australia's largest longitudinal cohort study of its kind. Following 10,000 WA children from their time in the womb into early childhood, ORIGINS researchers are working to better understand when and why non-communicable diseases develop, and provide solutions for early intervention to ensure every child and family flourishes throughout their lifetime.

The Flourishing Child: Study Protocol for an Acceptability and Feasibility Trial of a Digital Early Childhood Flourishing Intervention

Globally, rates of children with physical and mental health problems are increasing. Health issues in early childhood often persist into adulthood, highlighting the need to ensure children are supported to flourish from the start of life. 

Impaired calcium influx underlies skewed T helper cell differentiation in children with IgE-mediated food allergies

Reasons for Th2 skewing in IgE-mediated food allergies remains unclear. Clinical observations suggest impaired T cell activation may drive Th2 responses evidenced by increased atopic manifestations in liver transplant patients on tacrolimus (a calcineurin inhibitor). We aimed to assess differentiation potential, T cell activation and calcium influx of naïve CD4+ T cells in children with IgE-mediated food allergies. 

Influence of maternal and infant technology use and other family factors on infant development

Steve Desiree Zubrick Silva FASSA, FAAMHS, MSc AM PhD MBBS, FRACP, MPH, PhD Honorary Emeritus Research Fellow Co-Director, ORIGINS 08 6319 1409

Macronutrients in Human Milk and Early Childhood Growth—Is Protein the Main Driver?

Infant growth trajectories reflect current health status and may predict future obesity and metabolic diseases. Human milk is tailored to support optimal infant growth. However, nutrient intake rather than milk composition more accurately predicts growth outcomes. Although the role of protein leverage in infant growth is unclear, protein intake is important for early infancy growth.

Increasing emergency department visits for anaphylaxis in very early childhood: A canary in the coal mine

The incidence of anaphylaxis is increasing globally in tandem with changing environmental and lifestyle factors. There is very limited data on very early childhood presentations. We aim to assess changes in rates, characteristics and management of infant anaphylaxis in a paediatric ED over a 15-year period.

Beyond Plants: The Ultra-Processing of Global Diets Is Harming the Health of People, Places, and Planet

Global food systems are a central issue for personal and planetary health in the Anthropocene. One aspect of major concern is the dramatic global spread of ultra-processed convenience foods in the last 75 years, which is linked with the rising human burden of disease and growing sustainability and environmental health challenges.