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Research
Rationale for use for monoclonal antibody and anti-cytokine therapy for multisystem inflammatory syndrome in children: A systematic reviewObjective: To review systematically the rationale for choice and use of monoclonal antibody and anti-cytokine therapy in multisystem inflammatory syndrome in children.
Research
Thoracic Society of Australia and New Zealand (TSANZ) position statement on chronic suppurative lung disease and bronchiectasis in children, adolescents and adults in Australia and New ZealandThis position statement, updated from the 2015 guidelines for managing Australian and New Zealand children/adolescents and adults with chronic suppurative lung disease (CSLD) and bronchiectasis, resulted from systematic literature searches by a multi-disciplinary team that included consumers.
Research
The effect of TNF treatment uptake on incident hospital admission in Western AustraliaTreatment strategies for juvenile idiopathic arthritis (JIA) have shifted significantly over the last 20 years. We examined the effect of the introduction of government-subsidised TNF inhibitor (TNFi) treatment on incident hospitalisation for JIA.
News & Events
The Impact of Poverty - interview with Steve ZubrickGrowing up poor is about more than just the size of your bank account. Read the new CoLab Impact of Poverty Evidence Report.
News & Events
The Kids welcomes State Government commitment to researchThe Kids Research Institute Australia, has welcomed the State Government's budget commitment to innovation and medical research.
News & Events
Grant to expand innovative consumer involvement programA $3.2 million grant from Lotterywest will allow the highly successful Consumer Involvement Program to be expanded to 18 other WA organisations.
News & Events
New blueprint for child health researchDelivering tangible and measurable improvements to the health and wellbeing of children is at the centre of a bold new blueprint for child health research in WA
News & Events
State Government boost for vital child health researchEight The Kids Research Institute Australia-led projects will benefit from a Western Australian Government boost to health research for the State’s children and young people.
Research
“Our kids are our future”: Barriers and facilitators to vaccine uptake and timeliness among Aboriginal children younger than five years in Boorloo (Perth), Western AustraliaRates of several vaccine preventable diseases, and associated hospitalisation, are higher among Aboriginal and/or Torres Strait Islander children than non-Indigenous children. Western Australia has among the lowest childhood vaccine coverage in Australia, particularly among Aboriginal and/or Torres Strait Islander children. Delayed vaccination is also more common in this population. This project aimed to understand the barriers and facilitators to vaccine uptake and timeliness among Aboriginal and/or Torres Strait Islander children aged under five years in Boorloo (Perth).
Research
Respiratory infection- and asthma-prone, low vaccine responder children demonstrate distinct mononuclear cell DNA methylation pathwaysnfants with frequent viral and bacterial respiratory infections exhibit compromised immunity to routine immunizations. They are also more likely to develop chronic respiratory diseases in later childhood. This study investigated the feasibility of epigenetic profiling to reveal endotype-specific molecular pathways with potential for early identification and immuno-modulation.