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Research
Sulfamethoxazole-Trimethoprim (Cotrimoxazole) for Skin and Soft Tissue Infections Including Impetigo, Cellulitis, and AbscessWe conducted a systematic review of clinical trials and observational studies that address the utility of SXT for SSTI treatment, caused by either GAS or MRSA
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Genome-Wide Analysis of Genetic Risk Factors for Rheumatic Heart Disease in Aboriginal Australians Provides Support for Pathogenic Molecular MimicryRheumatic heart disease (RHD) after group A streptococcus (GAS) infections is heritable and prevalent in Indigenous populations. Molecular mimicry between human and GAS proteins triggers proinflammatory cardiac valve-reactive T cells.
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Epidemiology and mortality of staphylococcus aureus Bacteremia in Australian and New Zealand childrenDescribe the epidemiology of Staphylococcus aureus bacteremia in children and adolescents younger than 18 years from Australia and New Zealand
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Improving cardiovascular outcomes among Aboriginal Australians: Lessons from research for primary carePrimary care practitioners have an important role in improving Aboriginal cardiovascular care outcomes
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Prospective cohort study of childhood behaviour problems and adolescent sexual risk-taking: Gender mattersThis study sought to determine relationships, by gender, between childhood behaviour problems and adolescent risky sexual behaviours and substance use.
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A Comparison of Pneumococcal Nasopharyngeal Carriage in Very Young Fijian Infants Born by Vaginal or Cesarean DeliveryPneumococcal nasopharyngeal carriage prevalence and density were higher in infants delivered vaginally compared with those delivered by cesarean birth
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Focused cardiac ultrasound screening for rheumatic heart disease by briefly trained health workers: A study of diagnostic accuracyEchocardiographic screening for rheumatic heart disease (RHD) can identify individuals with subclinical disease who could benefit from antibiotic prophylaxis.
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Preliminary consultation on preferred product characteristics of benzathine penicillin G for secondary prophylaxis of rheumatic feverA sample target product profile for reformulated benzathine penicillin G is presented
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The prevention, diagnosis and management of central venous line infections in childrenWith advancing paediatric healthcare, the use of central venous lines has become a fundamental part of management of neonates and children.
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Are minor echocardiographic changes associated with an increased risk of acute rheumatic fever or progression to rheumatic heart disease?We aimed to determine the significance of minor heart valve abnormalities, including Borderline RHD, in predicting the future risk of acute rheumatic fever.