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Prematurity-associated lung disease: is it asthma?Shannon Elizabeth Simpson Smith BMedSci (hons), PhD PhD, MSc, BSc Head, Strong Beginnings Research Program Manager 08 6319 1631 08 6319 1178
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Autism likelihood in infants born to mothers with asthma is associated with blood inflammatory gene biomarkers in pregnancyMothers with asthma or atopy have a higher likelihood of having autistic children, with maternal immune activation in pregnancy implicated as a mechanism. This study aimed to determine, in a prospective cohort of mothers with asthma and their infants, whether inflammatory gene expression in pregnancy is associated with likelihood of future autism.
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Food Allergy Genetics and Epigenetics: A Review of Genome-Wide Association StudiesIn this review, we provide an overview of food allergy genetics and epigenetics aimed at clinicians and researchers. This includes a brief review of the current understanding of genetic and epigenetic mechanisms, inheritance of food allergy, as well as a discussion of advantages and limitations of the different types of studies in genetic research.
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Does lung function in preschoolers help to predict asthma in later life?The earliest respiratory function assessments, within or close to the neonatal period, consistently show correlations with lung function and with the development of asthma into adulthood. Measurements of lung function in infancy reflect the in utero period of lung development, and if early enough, show little influence of postnatal environmental exposures.
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Decreased fibronectin production significantly contributes to dysregulated repair of asthmatic epitheliumIn human asthma, and experimental allergic airways disease in mice, antigen-presenting cells and CD4(+) effector cells at the airway mucosa orchestrate, and CD4
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A diagnostic test for scabies: IgE specificity for a recombinant allergen of Sarcoptes scabieiScabies infestations are difficult to diagnose clinically and current serologic tests have less than 50% accuracy...
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Homology modeling and monoclonal antibody binding of the der f 7 dust mite allergenThe group 7 allergens are important allergenic specificities for mite-sensitive patients and may need to be incorporated into new diagnostic and therapeutic...
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Responsiveness of the human airway in vitro during deep inspiration and tidal oscillationIn healthy individuals, deep inspiration produces bronchodilation and reduced airway responsiveness, which may be a response of the airway wall to mechanical...
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Responsiveness of the human airway in vitro during deep inspiration and tidal oscillationThe aim of this study was to examine the in vitro response of isolated human airways to the dynamic mechanical stretch associated with normal breathing.
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Elemental carbon exposure and lung function in schoolchildren from Mexico CityThough exposure to air pollution has a detrimental effect on respiratory health, few studies have examined the association between elemental carbon exposure...