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Using Systems Biology to understand asthma exacerbations and develop better treatments

Investigators: Alexander Larcombe, Anthony Bosco, Anthony Kicic, Deb Strickland, Emma De Jong, Jeff Lauzon-Joset, Patrick Holt, Peter Le Souef

Plain language summary: 

Our research using cutting-edge technology has demonstrated that not all asthma attacks are the same. There are two major subtypes of asthma attacks. Currently, we use the same medication to treat all asthma attacks, and this medication targets the symptoms rather than the cause. This research will conduct detailed laboratory studies to understand what causes the two different types of asthma attacks, and test new treatments that are targeted and tailored to each type of asthma attack.