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Update on total intravenous anesthesia in children

To summarize recent evidence in pediatric total intravenous anesthesia (TIVA), highlighting advances in pharmacokinetics-pharmacodynamics, target-controlled infusion (TCI), electroencephalography (EEG)-guided titration, emerging agents, safety, and sustainability, and to provide clinicians with an updated, practical framework for pediatric TIVA practice.

Citation:
Quintão VC, Carlos RV, von Ungern-Sternberg BS. Update on total intravenous anesthesia in children. Curr Opin Anaesthesiol. 2026.

Keywords:
drug dose– response relationship; intravenous anesthesia; pediatric anesthesia; perioperative complications; perioperative outcomes; sustainable development

Abstract:
To summarize recent evidence in pediatric total intravenous anesthesia (TIVA), highlighting advances in pharmacokinetics-pharmacodynamics, target-controlled infusion (TCI), electroencephalography (EEG)-guided titration, emerging agents, safety, and sustainability, and to provide clinicians with an updated, practical framework for pediatric TIVA practice.