Skip to content
The Kids Research Institute Australia logo
Donate

Discover . Prevent . Cure .

Skeletal muscle health in childhood cancer survivors: a systematic review and meta-analysis

Childhood cancer survivors (CCS) are at risk of long-term skeletal muscle deficits following intensive therapies during critical periods of growth. This review aimed to synthesize approaches for assessing muscle quantity, quality, and function in CCS and to quantify deficits relative to healthy peers. 

Citation:
Markarian AM, Taaffe DR, Galvão DA, …….. Gottardo NG, Dhamija M, et al. Skeletal muscle health in childhood cancer survivors: a systematic review and meta-analysis. Supportive Care Cancer. 2026;34(3).

Keywords:
Childhood cancer; Meta-analysis; Muscle function; Muscle quality; Muscle quantity; Systematic review

Abstract:
Childhood cancer survivors (CCS) are at risk of long-term skeletal muscle deficits following intensive therapies during critical periods of growth. This review aimed to synthesize approaches for assessing muscle quantity, quality, and function in CCS and to quantify deficits relative to healthy peers.