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Invasive mould infection in children – advances made or obstacles remaining?

Invasive mould infection (IMI) is a major cause of morbidity and mortality in immunocompromised children. Outcomes for paediatric patients with IMI remain poor, due in part to the limitations of available diagnostic tools and therapeutic agents.

Citation:
Yeoh DK, Butters C, Clark JE, ……. Blyth CC. Invasive mould infection in children – advances made or obstacles remaining? Clinical Microbiology and Infection. 2025.

Keywords:
Antifungals; Aspergillosis; Children; Diagnostic imaging; Fusariosis; Invasive fungal disease; Mucormycosis; Scedosporiosis

Abstract:
Invasive mould infection (IMI) is a major cause of morbidity and mortality in immunocompromised children. Outcomes for paediatric patients with IMI remain poor, due in part to the limitations of available diagnostic tools and therapeutic agents.