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Delayed airway epithelial repair is correlated with airway obstruction in young adults born very preterm

Nasal epithelial cells from young adults with a history of very preterm birth show delayed closure following scratch-wounding. Repair correlated with lung function, suggesting epithelial barrier integrity may play a role in preterm-associated lung disease.

Citation:
Evans DJ, Smith EF, Hemy NR, Gibbons JTD, Wilson AC, Kicic A, Simpson SJ. Delayed airway epithelial repair is correlated with airway obstruction in young adults born very preterm. ERJ Open Res. 2024:00816-2024

Abstract:
Nasal epithelial cells from young adults with a history of very preterm birth show delayed closure following scratch-wounding. Repair correlated with lung function, suggesting epithelial barrier integrity may play a role in preterm-associated lung disease.