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Time-course RNAseq data of murine AB1 mesothelioma and Renca renal cancer following immune checkpoint therapy

Time-critical transcriptional events in the immune microenvironment are important for response to immune checkpoint blockade (ICB), yet these events are difficult to characterise and remain incompletely understood. Here, we present whole tumor RNA sequencing data in the context of treatment with ICB in murine models of AB1 mesothelioma and Renca renal cell cancer. 

Citation:
Chin WL, Zemek RM, Tilsed CM, Forrest ARR, Fear VS, Forbes C, Boon L, ……. Lesterhuis WJ, Lassmann T. Time-course RNAseq data of murine AB1 mesothelioma and Renca renal cancer following immune checkpoint therapy. Sci Data. 2024;11(1):448.

Keywords:
Carcinoma; renal cell; genetics; kidney neoplasms; immune checkpoint inhibitors; mesothelioma; drug therapy; sequencing

Abstract:
Time-critical transcriptional events in the immune microenvironment are important for response to immune checkpoint blockade (ICB), yet these events are difficult to characterise and remain incompletely understood. Here, we present whole tumor RNA sequencing data in the context of treatment with ICB in murine models of AB1 mesothelioma and Renca renal cell cancer.