Ovulation induction and subfertile untreated conception groups offer improved options for interpreting risks associated with ART

To identify and characterise appropriate comparison groups for population studies of health outcomes in ART-conceived births: ovulation induction (OI), subfertile untreated and fertile natural conceptions. Our secondary objective was to examine whether known risks of pregnancy complications and adverse birth outcomes in ART births are elevated in comparison with subfertile (untreated and OI) conception groups.

Citation:
Hansen M, Hart RJ, Milne E, Bower C, Walls ML, et al. Ovulation induction and subfertile untreated conception groups offer improved options for interpreting risks associated with ART. J Assisted Reprod Genet. 2024;41(4):915-928.

Keywords:
ART outcomes; Assisted reproductive technology; IVF; Ovulation induction; Subfertility

Abstract:
To identify and characterise appropriate comparison groups for population studies of health outcomes in ART-conceived births: ovulation induction (OI), subfertile untreated and fertile natural conceptions. Our secondary objective was to examine whether known risks of pregnancy complications and adverse birth outcomes in ART births are elevated in comparison with subfertile (untreated and OI) conception groups.