Design and selection of drug properties to increase the public health impact of next-generation seasonal malaria chemoprevention: a modelling study

Seasonal malaria chemoprevention (SMC) is recommended for disease control in settings with moderate to high Plasmodium falciparum transmission and currently depends on the administration of sulfadoxine-pyrimethamine plus amodiaquine.

Citation:
Braunack-Mayer L, Malinga J, …….. Penny MA. Design and selection of drug properties to increase the public health impact of next-generation seasonal malaria chemoprevention: a modelling study. Lancet Global Health. 2024;12(3):e478-e90

Keywords:
Antimalarials; pharmacology; therapeutic use; chemoprevention; malaria; drug therapy; epidemiology

Abstract:
Seasonal malaria chemoprevention (SMC) is recommended for disease control in settings with moderate to high Plasmodium falciparum transmission and currently depends on the administration of sulfadoxine-pyrimethamine plus amodiaquine.