Intake of polyphenols from cereal foods and colorectal cancer risk in the Melbourne Collaborative Cohort Study

Cereal-derived polyphenols have demonstrated protective mechanisms in colorectal cancer (CRC) models; however, confirmation in human studies is lacking. Therefore, this study examined the association between cereal polyphenol intakes and CRC risk in the Melbourne Collaborative Cohort Study (MCCS), a prospective cohort study in Melbourne, Australia that recruited participants between 1990 and 1994 to investigate diet-disease relationships.

Citation:
Vingrys K, Mathai ML, McAinch AJ, ……. Millar L, Giles GG, et al. Intake of polyphenols from cereal foods and colorectal cancer risk in the Melbourne Collaborative Cohort Study. Cancer Med. 2023

Keywords:
Melbourne Collaborative Cohort Study; cereals; colorectal cancer; food frequency questionnaire; polyphenols

Abstract:
Cereal-derived polyphenols have demonstrated protective mechanisms in colorectal cancer (CRC) models; however, confirmation in human studies is lacking. Therefore, this study examined the association between cereal polyphenol intakes and CRC risk in the Melbourne Collaborative Cohort Study (MCCS), a prospective cohort study in Melbourne, Australia that recruited participants between 1990 and 1994 to investigate diet-disease relationships.