Citation:
Gould JF, Makrides M, Gibson RA, ……… Simmer K, Doyle LW, Collins CT. Neonatal Docosahexaenoic Acid in Preterm Infants and Intelligence at 5 Years. N Engl J Med. 2022;387(17):1579-88.
Keywords:
Bronchopulmonary Dysplasia, prevention & control; Dietary Supplements/adverse effects; Docosahexaenoic Acids, deficiency/pharmacology/therapeutic use; Emulsions; Follow-Up Studies; Premature/growth & development; Intelligence/drug effects
Abstract
Docosahexaenoic acid (DHA) is a component of neural tissue. Because its accretion into the brain is greatest during the final trimester of pregnancy, infants born before 29 weeks' gestation do not receive the normal supply of DHA. The effect of this deficiency on subsequent cognitive development is not well understood.