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Identifying gene network patterns and associated cellular immune responses in children with or without nut allergy

Although evidence suggests that the immune system plays a key role in the pathophysiology of nut allergy, the precise immunological mechanisms of nut allergy have not been systematically investigated. The aim of the present study was to identify gene network patterns and associated cellular immune responses in children with or without nut allergy.

Citation:
Lee KH, Bosco A, O'Sullivan M, Song Y, Metcalfe J, Yu K, et al. Identifying gene network patterns and associated cellular immune responses in children with or without nut allergy. World Allergy Organ J. 2022;15(2).

Keywords:
Biomarker; Food allergy; Nut allergy; RNA sequencing; RT-qPCR; WGCNA

Abstract:
Although evidence suggests that the immune system plays a key role in the pathophysiology of nut allergy, the precise immunological mechanisms of nut allergy have not been systematically investigated. The aim of the present study was to identify gene network patterns and associated cellular immune responses in children with or without nut allergy.