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Performance of antigen detection for HRP2-based malaria rapid diagnostic tests in community surveys: Tanzania, July–November 2017

Malaria rapid diagnostic tests (RDTs) based on the detection of the Plasmodium falciparum histidine-rich protein 2 (HRP2) antigen are widely used for detection of active infection with this parasite and are the only practical malaria diagnostic test in some endemic settings.

Citation:
Rogier E, Bakari C, Mandara CI, ……. Rumisha SF, Molteni F,et al. Performance of antigen detection for HRP2-based malaria rapid diagnostic tests in community surveys: Tanzania, July–November 2017. Malar J. 2022;21(1)

Keywords:
Histidine-rich protein 2; Limit of detection Plasmodium falciparum; Malaria; Rapid diagnostic tests; Tanzania; antigen; histidine;
blood sampling; community care; controlled study; correlation analysis; cross-sectional study; diagnostic test accuracy study

Abstract:
Malaria rapid diagnostic tests (RDTs) based on the detection of the Plasmodium falciparum histidine-rich protein 2 (HRP2) antigen are widely used for detection of active infection with this parasite and are the only practical malaria diagnostic test in some endemic settings.