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Effect of Preemptive Intervention on Developmental Outcomes Among Infants Showing Early Signs of Autism: A Randomized Clinical Trial of Outcomes to Diagnosis

Intervention for individuals with autism spectrum disorder (ASD) typically commences after diagnosis. No trial of an intervention administered to infants before diagnosis has shown an effect on diagnostic outcomes to date.

Citation:
Whitehouse AJO, Varcin KJ, Pillar S, Billingham W, Alvares GA, Barbaro J, ….. Boutrus M, Chee A, Chetcuti L, Clark A, …….. Harrap M, Iacono T, Matys L, Maybery M, Pope DF, Renton M, …...… Cooper M, et al. Effect of Preemptive Intervention on Developmental Outcomes Among Infants Showing Early Signs of Autism: A Randomized Clinical Trial of Outcomes to Diagnosis. JAMA Pediatr. 2021:e213298.

Keywords:
ASD; Autism; randomised clinical trial

Abstract:
Intervention for individuals with autism spectrum disorder (ASD) typically commences after diagnosis. No trial of an intervention administered to infants before diagnosis has shown an effect on diagnostic outcomes to date.