Echinocandins in Pediatric Invasive Candidiasis and the Challenges of Antifungal Use in Children

In pediatric invasive candidiasis (IC), epidemiology and risk factors differ compared to adults. Furthermore, the use of antifungals in children is challenging and requires consideration of availability and tolerability of formulations, pharmacokinetic and pharmacodynamic variations, and safety in different age groups.

Citation:
Yeoh DK, Blyth CC, McMullan BJ. Echinocandins in Pediatric Invasive Candidiasis and the Challenges of Antifungal Use in Children. J Pediatric Infect Dis Soc. 2021;10(7):755-6.

Keywords:
Pediatric invasise candidiasis; epidemiology; randomised controlled trials

Abstract:
In pediatric invasive candidiasis (IC), epidemiology and risk factors differ compared to adults. Furthermore, the use of antifungals in children is challenging and requires consideration of availability and tolerability of formulations, pharmacokinetic and pharmacodynamic variations, and safety in different age groups.