The Kids Research Institute Australia logo
Donate

Discover Prevent Cure

Exploiting the reactive oxygen species imbalance in high-risk paediatric acute lymphoblastic leukaemia through auranofin

The prognosis for high-risk childhood acute leukaemias remains dismal and established treatment protocols often cause long-term side effects in survivors. This study aims to identify more effective and safer therapeutics for these patients.

Citation:
Karsa M, Kosciolek A, Bongers A, Mariana A, ..... Kees UR, Cheung LC, Kotecha RS, et al. Exploiting the reactive oxygen species imbalance in high-risk paediatric acute lymphoblastic leukaemia through auranofin. Br J Cancer. 2021.

Keywords:
Auranofin; paediatric and adult acute leukaemia

Abstract:
The prognosis for high-risk childhood acute leukaemias remains dismal and established treatment protocols often cause long-term side effects in survivors. This study aims to identify more effective and safer therapeutics for these patients.