Citation:
Read JF, Bosco A. Decoding Susceptibility to Respiratory Viral Infections and Asthma Inception in Children. Int J Mol Sci. 2020;21(17):1-19.
Keywords: Bow-tie architecture; Human Rhinovirus; asthma; early life; innate immunity; multi-omics; omics; respiratory syncytial virus; systems biology; wheeze.
Abstract:
Human Respiratory Syncytial Virus and Human Rhinovirus are the most frequent cause of respiratory tract infections in infants and children and are major triggers of acute viral bronchiolitis, wheezing and asthma exacerbations. Here, we will discuss the application of the powerful tools of systems biology to decode the molecular mechanisms that determine risk for infection and subsequent asthma.
Decoding Susceptibility to Respiratory Viral Infections and Asthma Inception in Children
Human Respiratory Syncytial Virus and Human Rhinovirus are the most frequent cause of respiratory tract infections in infants and children and are major triggers of acute viral bronchiolitis, wheezing and asthma exacerbations.