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Bile Acid Signal Molecules Associate Temporally with Respiratory Inflammation and Microbiome Signatures in Clinically Stable Cystic Fibrosis Patients

Cystic fibrosis (CF) is a congenital disorder resulting in a multisystemic impairment in ion homeostasis. The subsequent alteration of electrochemical gradients severely compromises the function of the airway epithelia.

Citation:
Flynn S, Reen FJ, Caparros-Martin JA, Woods DF, Peplies J, Ranganathan SC, Stick SM, O'Gara F. Bile Acid Signal Molecules Associate Temporally with Respiratory Inflammation and Microbiome Signatures in Clinically Stable Cystic Fibrosis Patients. Microorg. 2020;8(11):1-17.

Keywords:
Bile acids; cystic fibrosis; gut-lung axis; inflammation; lung microbiota

Abstract:
Cystic fibrosis (CF) is a congenital disorder resulting in a multisystemic impairment in ion homeostasis. The subsequent alteration of electrochemical gradients severely compromises the function of the airway epithelia.