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The western dietary pattern is prospectively associated with nonalcoholic fatty liver disease in adolescence

In centrally obese adolescents with NAFLD, a healthy dietary pattern may be protective, whereas a Western dietary pattern may increase the risk.

Authors:
Oddy WH, Herbison CE, Jacoby P, Ambrosini GL, O'Sullivan TA, Ayonrinde OT, Olynyk JK, Black LJ, et al. 

Authors notes:
American Journal of Gastroenterology. 2013;108(5):778-785

Keywords:
Diet, nonalcoholic fatty liver disease, adolescents, dietary pattern, healthy diet

Abstract:
Poor dietary habits have been implicated in the development of nonalcoholic fatty liver disease (NAFLD); however, little is known about the role of specific dietary patterns in the development of NAFLD.

We examined prospective associations between dietary patterns and NAFLD in a population-based cohort of adolescents.

NAFLD was present in 15.2% of adolescents.

A higher Western dietary pattern score at 14 years was associated with a greater risk of NAFLD at 17 years, although these associations were no longer significant after adjusting for body mass index at 14 years.

However, a healthy dietary pattern at 14 years appeared protective against NAFLD at 17 years in centrally obese adolescents, whereas a Western dietary pattern was associated with an increased risk of NAFLD.

A Western dietary pattern at 14 years in a general population sample was associated with an increased risk of NAFLD at 17 years, particularly in obese adolescents.

In centrally obese adolescents with NAFLD, a healthy dietary pattern may be protective, whereas a Western dietary pattern may increase the risk.