Authors:
Smart CEM, Evans M, O'Connell SM, McElduff P, Lopez PE, Jones TW, Davis EA, King BR
Authors notes:
Diabetes Care. 2013;36(12):3897-3902.
Keywords:
Type 1 diabetes, diet, high protein, high fat, glycaemia, glucose excursions
Abstract:
Our objective was to determine the separate and combined effects of high-protein (HP) and high-fat (HF) meals, with the same carbohydrate content, on postprandial glycemia in children using intensive insulin therapy (IIT).
Compared with the LF/LP meal, mean glucose excursions were greater from 180 min after the LF/HP meal and from 210 min after the HF/LP meal.
The HF/HP meal resulted in higher glucose excursions from 180 min to 300 min compared with all other meals.
There was a reduction in the risk of hypoglycemia after the HP meals (odds ratio 0.16.
Meals high in protein or fat increase glucose excursions in youth using IIT from 3 h to 5 h postmeal.
Protein and fat have an additive impact on the delayed postprandial glycemic rise.
Protein had a protective effect on the development of hypoglycemia.