Promoter polymorphisms in two overlapping 6p25 genes implicate mitochondrial proteins in cognitive deficit in schizophrenia

In a previous study, we detected a 6p25-p24 region linked to schizophrenia in families with high composite cognitive deficit (CD) scores, a quantitative trait..

Authors:
Jablensky A, Angelicheva D, Donohoe GJ, Cruickshank M, Azmanov DN, Morris DW, McRae A, Weickert CS, Carter KW, et al

Authors notes:
Molecular Psychiatry Oct 4. doi: 10.1038/mp.2011.129

Keywords:
Promoter polymorphisms, two overlapping 6p25 genes, implicate mitochondrial proteins, cognitive deficit in schizophrenia

Abstract
In a previous study, we detected a 6p25-p24 region linked to schizophrenia in families with high composite cognitive deficit (CD) scores, a quantitative trait integrating multiple cognitive measures.