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High tidal volume ventilation is not deleterious in infant rats exposed to severe hemorrhage

Both high tidal volume (V(T)) ventilation and hemorrhage induce acute lung injury in adult rodents. It is not known whether injurious ventilation augments lung

Authors:
Cannizzaro V, Berry LJ, Nicholls PK, Hantos Z, Sly PD

Journal of Trauma 2010;69:E24-31

Keywords:
High tidal volume ventilation, not deleterious, infant rats, exposed to severe hemorrhage

Abstract:
Both high tidal volume (V(T)) ventilation and hemorrhage induce acute lung injury in adult rodents. It is not known whether injurious ventilation augments lung injury in infant rats exposed to severe hemorrhage.