1,25-dihydroxyvitamin D3 enhances the ability of transferred CD4+ CD25+ cells to modulate T helper type 2-driven asthmatic responses

The severity of allergic diseases may be modified by vitamin D. However, the immune pathways modulated by the active form of vitamin D, 1,25-dihydroxyvitamin D.

Authors:
Gorman S, Judge MA, Burchell JT, Turner DJ, Hart PH

Authors notes:
Immunology 2010 Jun;130:181-92

Keywords:
1,25-dihydroxyvitamin D3, transferred CD4+ CD25+ cells to modulate T helper type 2-driven asthmatic responses

Abstract
The severity of allergic diseases may be modified by vitamin D. However, the immune pathways modulated by the active form of vitamin D, 1,25-dihydroxyvitamin D(3) [1,25(OH)(2)D(3)], are yet to be fully elucidated.