Detecting genotyping error using measures of degree of Hardy-Weinberg disequilibrium - art. no. 5

Tests for Hardy-Weinberg equilibrium (HWE) have been used to detect genotyping error, but those tests have low power unless the sample size is very large.

Authors:
Attia J, Thakkinstian A, McElduff P, Milne E, Dawson S, Scott RJ, de Klerk N, Armstrong B, Thompson J.

Authors notes:
Statistical Applications in Genetics and Molecular Biology 2010;9:5-5.

Keywords:
genotyping, Hardy-Weinberg disequilibrium

Abstract:
Tests for Hardy-Weinberg equilibrium (HWE) have been used to detect genotyping error, but those tests have low power unless the sample size is very large.

Detecting genotyping error using measures of degree of Hardy-Weinberg disequilibrium - art. no. 5

Authors:Attia J, Thakkinstian A, McElduff P, Milne E, Dawson S, Scott RJ, de Klerk N, Armstrong B, Thompson J.

Authors notes:Statistical Applications in Genetics and Molecular Biology 2010;9:5-5.

Keywords:genotyping, Hardy-Weinberg disequilibrium

Abstract:Tests for Hardy-Weinberg equilibrium (HWE) have been used to detect genotyping error, but those tests have low power unless the sample size is very large.

Authors:
Attia J, Thakkinstian A, McElduff P, Milne E, Dawson S, Scott RJ, de Klerk N, Armstrong B, Thompson J.

Authors notes:
Statistical Applications in Genetics and Molecular Biology 2010;9:5-5.

Keywords:
genotyping, Hardy-Weinberg disequilibrium

Abstract:
Tests for Hardy-Weinberg equilibrium (HWE) have been used to detect genotyping error, but those tests have low power unless the sample size is very large.