Authors:
Quanjer PH, Stanojevic S, Stocks J, Hall GL, Prasad KV, Cole TJ, Rosenthal M, Perez-Padilla R, Hankinson JL, Falaschetti E, Golshan M, Brunekreef B, Al-Rawas O, Kühr J, Trabelsi Y, Ip MS; Global Lungs Initiative.
Authors notes:
Eur Respir J. 2010 Dec;36(6):1391-9. Epub 2010 Mar 29.
Keywords:
changes, FEV/FVC ratio, childhood, adolescence, intercontinental study
Abstract:
In children, the ratio of forced expiratory volume in 1 s (FEV₁) to forced vital capacity (FVC) is reportedly constant or falls linearly with age, whereas the ratio of residual volume (RV) to total lung capacity (TLC) remains constant. This seems counter-intuitive given the changes in airway properties, body proportions, thoracic shape and respiratory muscle function that occur during growth.