Method of bacterial killing differentially affects the human innate immune response to Staphylococcus epidermidis

In vitro investigations of human innate immune responses to extracellular bacteria commonly utilise killed preparations in preference to live organisms

Authors:
Strunk T, P. Richmond, A. Prosser, K. Simmer, O. Levy, D. Burgner and A. Currie

Authors notes:
Innate Immun. 2011;17(6):508-16. Epub 2010 Aug 31

Keywords:
bacterial killing differentially, human innate, immune response, Staphylococcus epidermidis, extracellular bacteria, live organisms,

Abstract:
In vitro investigations of human innate immune responses to extracellular bacteria commonly utilise killed preparations in preference to live organisms. The effects of the bacterial preparation method on the activation of innate signalling pathways by the common opportunistic pathogen Staphylococcus epidermidis (SE) are unknown