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SJ-ELiOT: St Jude - Phase 1 Evaluation of LY2606368, Molecularly-Targeted CHK1/2i Therapy, in Combination with Cyclophosphamide or Gemcitabine for Children and Adolescents with Refractory or Recurrent Medulloblastoma Brain Tumours

Nick Raelene Gottardo Endersby MBChB FRACP PhD BSc (Hons) PhD Co-Head, Brain Tumour Research team; Head of Oncology and Haematology, Perth Children’s Hospital Brainchild Fellow; Co-Head, Brain Tumour Research team nicholas.gottardo@thekids.org.au

Sensitising glioblastoma to enhance cancer therapy

Raelene Nick Endersby Gottardo BSc (Hons) PhD MBChB FRACP PhD Brainchild Fellow; Co-Head, Brain Tumour Research team Co-Head, Brain Tumour Research team; Head of Oncology and Haematology, Perth Children’s Hospital raelene.endersby@thekids.org.au

Radiosensitisation of medulloblastoma

Raelene Nick Endersby Gottardo BSc (Hons) PhD MBChB FRACP PhD Brainchild Fellow; Co-Head, Brain Tumour Research team Co-Head, Brain Tumour Research team; Head of Oncology and Haematology, Perth Children’s Hospital raelene.endersby@thekids.org.au

Exploring the immune microenvironment and investigating novel immunotherapeutics for medulloblastoma and paediatric high-grade glioma

Raelene Nick Endersby Gottardo BSc (Hons) PhD MBChB FRACP PhD Brainchild Fellow; Co-Head, Brain Tumour Research team Co-Head, Brain Tumour Research team; Head of Oncology and Haematology, Perth Children’s Hospital raelene.endersby@thekids.org.au

Chemosensitisation of medulloblastoma and pineoblastoma

Raelene Nick Endersby Gottardo BSc (Hons) PhD MBChB FRACP PhD Brainchild Fellow; Co-Head, Brain Tumour Research team Co-Head, Brain Tumour Research team; Head of Oncology and Haematology, Perth Children’s Hospital raelene.endersby@thekids.org.au